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Middleware Software Engineer at Symmetrio. Symmetrio is recruiting a Senior Middleware Software Engineer for our customer, a global conglomerate in the medical device space. This engineer will play a pivotal role in connecting embedded firmware systems with higher-level software applications and clinical platforms. The ideal candidate will bring a strong background in C#, Visual Studio, .NET, API development, and real-time device communication, ideally within a regulated medical environment. This role is part of a highly collaborative engineering team focused on developing advanced technology for critical applications in the healthcare space. It offers a unique opportunity to work at the intersection of software, hardware, and real-time data systems.. Remote candidates will be considered but preference will be given to those located in Florida. Salary range is $125–160k depending on experience.. Remote candidates will be considered but preference will be given to those located in Florida. Salary range is $125-160k depending on experience.. Responsibilities. . Design, develop, and maintain ASP.NET Web API applications for ingesting, processing, and exposing data from medical hardware systems. . . Integrate with hardware device APIs to collect, measure, and analyze ionizing radiation data for quality assurance. . . Implement real-time data streaming using SignalR, allowing clinicians and systems to interact with live device data. . . Maintain and improve Windows Communication Foundation (WCF) services and Windows Services for reliable transmission of data from distributed devices to on-prem servers. . . Build and optimize data storage/retrieval workflows using Entity Framework with SQL Server and MongoDB, including writing and optimizing SQL queries. . . Collaborate with firmware, hardware, software, and medical physics teams to identify system-level requirements and troubleshoot integration issues. . . Develop internal tools and utilities, potentially using WPF, to support operations and product diagnostics. . . Ensure all middleware components comply with FDA regulations and industry standards like IEC 62304, DICOM, and HL7. . . Participate in design reviews, risk analysis, and support testing and documentation required for regulated environments. . . Serve as a technical escalation point for product support teams. . . . 7+ years of experience in middleware, backend, or systems software engineering . . Highly proficient in C#, Visual Studio, and .NET, including ASP.NET Web API and WCF.. . Strong understanding of HTTP methods, Web APIs, and REST principles. . . Experience developing and maintaining Windows Services. . . Experience integrating with hardware or embedded systems APIs. . . Proficiency with Entity Framework, SQL Server, and MongoDB, including writing and optimizing SQL queries. . . Experience with real-time communication using SignalR or similar frameworks. . . Familiarity with JSON and XML for data exchange and parsing. . . Prior work with medical devices, oncology/radiation systems, or other regulated industries. . . Strong testing and debugging skills across software and hardware boundaries. . . Excellent documentation practices and communication skills. . . Preferred. . Background in radiation oncology, medical physics, or QA of therapy devices . . Experience developing or supporting dose calibrators, PACS/RIS, or clinical QA software . . Understanding of FDA 21 CFR Part 820, ISO 13485, IEC 62304, or similar compliance frameworks . . Prior experience delivering Tier 2 support or collaborating with R&D and product teams . . Company Location: United States.