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Full-Stack Software Engineer (Python + React) (HealthTech/AI) - A136 at Pearl. Work Arrangement:. Remote or In-Person (New York City, NY). Job Type:. Independent Contractor, Full-time. Work Schedule:. Monday to Friday | 40 hours. Locations:. United States (NYC preferred) . Open to remote candidates with overlapping U.S. hours . About Pearl Talent. Pearl works with the top 1% of candidates from around the world and connects them with the best startups in the US and EU. Our clients have raised over $5B in aggregate and are backed by companies like OpenAI, a16z, and Founders Fund. They’re looking for the sharpest, hungriest candidates who they can consistently promote and work with over many years. Candidates we’ve hired have been flown out to the US and EU to work with their clients, and even promoted to roles that match folks onshore in the US.. Hear why we exist, what we believe in, and who we’re building for: . WATCH HERE. Why Work with Us?. At Pearl, we’re not just another recruiting firm—we connect you with exceptional opportunities to work alongside visionary US and EU founders. Our focus is on placing you in roles where you can grow, be challenged, and build long-term, meaningful careers.. Role Overview. We’re seeking a . Senior Full-Stack Software Engineer. to join a fast-growing AI-driven HealthTech startup that’s redefining pharmacy automation. Their agentic AI platform is already deployed across multiple U.S. pharmacies, streamlining workflows and improving patient access and care.. As a Founding Engineer, you’ll collaborate directly with the founders to design, build, and scale the company’s AI infrastructure. You’ll work across the stack—from backend systems and LLM integrations to frontend product delivery—owning projects that make real-world clinical impact. This role is perfect for an engineer who thrives in early-stage, high-velocity environments and wants to help shape the future of healthcare technology.. Your Impact. You’ll be instrumental in building the technical foundation of a category-defining HealthTech startup. From architecting AI workflows that optimize pharmacy operations to ensuring scalable, HIPAA-compliant systems, your work will directly enhance patient outcomes and redefine what’s possible in digital healthcare.. Core Responsibilities. AI System Development & Integration – 30%. Design and implement AI-powered workflows for pharmacy operations. . Build and refine LLMs, agentic systems, and integrations that power patient and staff interactions. . Use prompt engineering and experimentation to optimize performance and contextual accuracy. . Backend Engineering & Infrastructure – 30%. Architect and scale backend systems using Python, TypeScript, and Postgres. . Develop APIs ensuring performance, security, and reliability. . Maintain CI/CD pipelines for safe, rapid deployment. . Ensure HIPAA-compliant infrastructure and data integrity. . Frontend & Product Collaboration – 20%. Build modern, responsive UIs with frameworks like React. . Partner with product and design teams to translate ideas into high-performing user experiences. . Establish continuous feedback loops with customers to refine product direction. . Scalability & System Reliability – 10%. Diagnose and optimize system bottlenecks to improve reliability and performance. . Implement monitoring and testing frameworks to ensure uptime and resilience. . Support integrations across both cloud and on-prem environments. . Strategic & Cross-Functional Collaboration – 10%. Contribute to the long-term technical roadmap and architecture decisions. . Mentor new engineers as the team scales. . Work directly with leadership to translate business goals into technical deliverables.. Must-Have (Required):. 4+ years of full-time software engineering experience (excluding internships). . Strong backend development experience with . Python, TypeScript, Postgres. , and . AWS. . . Hands-on experience with . LLMs, prompt engineering, or voice AI systems. (personal or production). . Proven success designing and scaling systems for production environments. . Prior experience in . startups or early-stage engineering teams. . . Strong communication and collaboration skills across technical and non-technical teams. . High ownership mindset and bias toward fast, iterative shipping. . Nice-to-Have (Preferred):. Prior experience as a founding engineer or technical lead in a startup. . Background in . healthtech, pharmacy tech, or clinical automation. . . Familiarity with . AI engineering tools. such as Copilot, Cursor, or Replit Ghostwriter. . Tools Proficiency. Required:. . Languages:. Python, JavaScript, TypeScript . . Backend:. FastAPI, Flask, Node.js . . Frontend:. React or modern JS frameworks . . Database:. PostgreSQL . . Infrastructure:. AWS (Lambda, EC2, S3), Docker . . AI Stack:. OpenAI APIs, LangChain, vector databases . . Version Control & CI/CD:. GitHub, CircleCI . Preferred:. HIPAA-compliant frameworks . Data encryption and security libraries . AI-powered productivity tools . Company Location: Colombia.